3-Mercaptopropionic Acid CAS 107-96-0

3-Mercaptopropionic acid, also known as mercaptopropionic acid, is an organic compound with important applications. It is a light yellow viscous liquid with a certain irritating odor. Easy to dissolve in organic solvents such as water, ethanol, ether, and chloroform, slightly soluble in benzene and petroleum ether. During the dissolution process, hydrogen bonding may occur, which can affect its solubility and crystallization behavior. Stable at room temperature, but prone to oxidation reactions in the presence of light, oxygen, and metal ions, generating corresponding disulfide compounds. It is an organic acid containing thiol (- SH) and has strong reducing properties. In chemical reactions, thiol groups can participate in various reactions, such as oxidation, reduction, addition, and substitution. Due to its strong reducibility, it can react with oxidants to form disulfides, and can also form insoluble metal complexes with metal ions. In addition, under alkaline conditions, self polymerization reactions can occur to form polymers. It also has some biological and biomedical properties. Due to its thiol group, it has reducing and nucleophilic properties and can bind with biomolecules such as heavy metal ions, proteins, and nucleic acids to form stable complexes. This property makes the product have important application value in the biomedical field, such as detoxification for heavy metal poisoning, protein purification, antibody labeling, and biosensors.

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(1) , acrylic acid is introduced into the gasification chamber according to the set flow rate, and hydrogen sulfide and acrylic acid are introduced into the mixer according to a certain molar ratio to mix evenly;

(2) Starting a plasma reactor filled with a catalyst, passing the mixed gas into the plasma reactor for reaction, and controlling the reaction temperature and pressure;

(3) After the reaction was completed, 3 mercaptopropionic acid was obtained by cooling and rectification

3-mercaptopropionic acid. The whole synthesis process is carried out at 0.05-0.1mpa. The process is simple and continuous operation can be realized. The experimental results show that the average yield of mercaptopropionic acid by the method provided by the present invention is 78.77%

3-Mercaptopropionic acid
1. In the field of medicine, its applications mainly include antibacterial, anti-inflammatory, and antiviral aspects. Due to its reducibility and nucleophilicity, it can bind with biomolecules such as heavy metal ions, proteins, and nucleic acids to form stable complexes, making it suitable for detoxification of heavy metal poisoning. In addition, mercaptopropionic acid can also be used to prepare antibacterial and anti-inflammatory drugs, such as semi synthetic derivatives of cephalosporin C.
2. Its application in the industrial field is very extensive, and its important role is mainly reflected in metal processing, electroplating, and chemical synthesis. in the field of electroplating, mercaptopropionic acid also plays an important role. During the electroplating process, various additives are needed to improve the uniformity and adhesion of the coating. Mercaptopropionic acid, as a commonly used additive, can react with metal ions to form insoluble metal complexes, increasing the adhesion between the coating and the substrate metal, thereby improving the quality of electroplating.
3. The application in the field of biotechnology is widespread and important, mainly including protein purification, antibody labeling, and biosensors.
(1) Firstly, the application of mercaptopropionic acid in protein purification has significant advantages. Proteins are important functional molecules in living organisms, but their separation and purification processes are often affected by various factors. Mercaptopropionic acid has reducing and nucleophilic properties, and can bind with biomolecules such as heavy metal ions, proteins, and nucleic acids to form stable complexes. This characteristic makes mercaptopropionic acid an effective protein purification agent. During protein purification, mercaptopropionic acid can separate target proteins from complex biological samples by forming insoluble precipitates or reversible complexes with proteins. This separation method has the advantages of high efficiency, high selectivity, and ease of operation, thus it has been widely applied in the field of biotechnology.
(2) Secondly, the application of mercaptopropionic acid in antibody labeling is also of great significance. Antibodies are biomolecules with specific recognition functions, widely used in biomedical research and clinical diagnosis. In order to achieve sensitive detection and quantitative analysis of biomolecules, it is often necessary to label antibodies. Mercaptopropionic acid, as an organic compound containing thiol groups, can covalently bind with antibodies to form stable markers. This labeling method not only maintains the biological activity of antibodies, but also provides high labeling efficiency and stability. By combining with other fluorescent dyes, radioactive isotopes, or enzyme markers, mercaptopropionic acid can achieve multifunctionality towards antibodies, further enhancing its application value in the biomedical field.
(3) In addition, the application of mercaptopropionic acid in biosensors has also received much attention. A biosensor is a device that can monitor the concentration and activity of biomolecules in real-time, with advantages such as high sensitivity, good selectivity, and fast response speed. Mercaptopropionic acid can form stable complexes with biomolecules, making it a recognition element for biosensors. Specific recognition and quantitative detection of target biomolecules can be achieved by modifying mercaptopropionic acid on the surface of the sensor or as part of the sensor. This application provides effective technical means for biomedical research, environmental monitoring, and food safety.
4. In the field of biotechnology, applications mainly include protein purification, antibody labeling, and biosensors. Due to its reducing and nucleophilic properties, mercaptopropionic acid can bind with biomolecules such as heavy metal ions, proteins, and nucleic acids to form stable complexes, making it suitable for protein purification and separation. In addition, mercaptopropionic acid can also be used to prepare antibody labels and biosensors for detecting the presence and concentration of biomolecules.

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